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Pistons vs Pelicans predictions, picks and odds for tonight’s NBA game

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The red-hot Detroit Pistons will look to extend their winning streak to four games tonight as they visit the last-place New Orleans Pelicans at the Smoothie King Center.

Cade Cunningham’s assist total is extremely high, but my Pistons vs. Pelicans predictions have him breaking down a terrible New Orleans defense.

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Find out more in my NBA picks for Wednesday, January 21.

Pistons vs Pelicans prediction

The best bet between Pistons and Pelicans: Cade Cunningham Over 10.5 assists (+102)

While the Detroit Pistons are a well-oiled machine, Cade Cunningham is undoubtedly the focal point of this team, leading the way with 25.7 points, 9.8 assists, and 5.9 rebounds per game. The former first overall pick is an incredible playmaker and ranks second in the Association in dimes.

No matter the opponent, Cunningham finds a way to facilitate rock at a high level. The guard has had over 10 assists in four of his last six outings, and he scored just 14 dimes against the Boston Celtics on Monday.

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Cunningham faces a poor New Orleans Pelicans perimeter defense that allows over nine assists a night to point guards, and they are considered an easy matchup at the position. Additionally, NOLA gives up 28.9 dimes per contest overall, second-worst in the NBA.

He will cook tonight as a passerby.

This is the same Pistons vs Pelicans game

Jalen Duren is a physical specimen from deep, and is proving to be an irreplaceable piece for the Pistons on both ends of the court. On the boards, Duren is a monster and averages 10.7 rebounds per game.

Even though Duren has cashed the over only once in his last four appearances, he faces a Pelicans team that gives up over 15 boards a night to centers. Duren takes advantage and has a great game on the glass.

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Trey Murphy is one of the only bright spots for the Pels. He’s averaging a career-best 22.2 points, and the University of Virginia product is cooking in January.

This month, Murphy is averaging 29.1 PPG. He hit the over in runs in eight consecutive games and during that time Murphy had three 30+ performances and also a 42-point outburst.

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Pistons vs Pelicans SGP

  • Cade Cunningham Over 10.5 assists

  • Jalen Duren Over 10.5 rebounds

  • Trey Murphy Over 20.5 points

Our SGP “from the center”: Robinson great

Duncan Robinson is on fire from deep right now, cashing in the over with triples made in five straight games.

Pistons vs Pelicans SGP

  • Cade Cunningham Over 10.5 assists

  • Jalen Duren Over 10.5 rebounds

  • Trey Murphy Over 20.5 points

  • Duncan Robinson Over 2.5 threes

Pistons vs Pelicans betting

  • Diffusion: Pistons -9.5 | Pelicans +9.5

  • Moneyline: Pistons -420 | Pelicans +330

  • Above/Below: Over 234.5 | Below 234.5

Pistons vs Pelicans betting trend to know

The Pistons have reached the Moneyline in 31 of their last 40 games (+16.70 units / 16% ROI). Check out more NBA betting trends for Pistons vs. Pelicans.

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How to watch Pistons vs Pelicans

Position

Smoothie King Center, New Orleans, LA

Date

Wednesday 21 January 2026

Suggestion

8pm ET

TV

FDSN Detroit, GCSEN

Latest injuries between Pistons and Pelicans

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This article originally appeared on Covers.com, read the full article here

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