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Knicks vs 76ers – Game 2 NBA Playoffs – predictions: odds, recent statistics, trends, best bets for May 6

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The New York Knicks swept the Philadelphia 76ers in Game 1, 137-98, 35 points behind Jalen Brunson (27 in the first half). New York has won four consecutive playoff games by 16, 29, 51 and 39 points.

Philadelphia played Game 7 in Boston on Saturday, then had a day off before playing Game 1 in New York on Monday. It’s not surprising that the 76ers were eliminated, but they’ll need a full 60-minute effort in Game 2 to avoid going back to Philadelphia in the hole. The 76ers shot 41% from the field in Game 1, turned the ball over 19 times and lost the rebounding battle (38-29). No one reached 20 points for the 76ers, but the good news is they shot 34 free throws to the Knicks’ 17 and no starter played more than 28 minutes for Philadelphia.

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New York is the hottest team in the Eastern Conference playoffs, unless you’re a Detroit Pistons fan. However, the Knicks’ four-game winning streak of 33.7 points per game has been dominant. The Knicks shot 63 percent from the field and 51 percent from three in Game 1. Four of the Knicks’ starters scored 18 or more points and together they shot 70.2 percent from the field (33/47) and 61.1 percent from three (11/18). They will look to continue that shootout in Game 2 at Madison Square Garden before heading to Philadelphia for Games 3 and 4.

Let’s take a closer look at tonight’s matchup and take into consideration lineups, injuries and other factors that affect the line and total.

We’ve got all the information and analysis you need to know ahead of the game, including the latest information on how to get tip-offs, odds courtesy of DraftKings recent team performances, player statistics and of course our predictions, select the best bets for the game from our modeling tools and expert staff.

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Game details and how to watch live: 76ers vs. Knicks

  • Date: Wednesday 6 May 2026

  • Site: Madison Square Garden

Rotoworld has you covered with all the latest news NBA player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Game Odds: 76ers vs. Knicks

Latest Wednesday odds courtesy of DraftKings:

  • Moneyline: Philadelphia 76ers (+220), New York Knicks (-270)

This game the Knicks opened at -7.5 with the total set at 216.5.

Be sure to check it out DraftKings for all the latest game odds and player tips for every game this week on the NBA schedule!

Predicted starting lineups: Knicks vs. 76ers

Philadelphia 76ers

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New York Knicks

Injury Report: Knicks vs. 76ers

New York Knicks

Philadelphia 76ers

  • Joel Embiid (ankle) is listed as PROBABLE for Game 2

Important stats, trends and insights: 76ers vs. Knicks

  • New York is 49-41 ATS and 48-42 Under this season

  • New York is 30-14 ATS at home, in first place

  • New York is 23-21 at home against the Under

  • Philadelphia is 27-19 ATS as a road team

  • Philadelphia is 14-14 ATS and 11-17 on the ML as a road underdog

  • Philadelphia is 49-42 ATS

  • Philadelphia is 48-43 Under and 24-21 Under on the road

Rotoworld best bet

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Our model calculates projections on every moneyline, spread and over/under bet for every game on the NBA schedule based on data such as recent performances, head-to-head player comparisons, trend information and projected game totals.

Once the model has finished running, we place its projections next to the final betting lines for the game to arrive at a relative confidence level for each bet.

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Here are the best bets predicted by our model for Wednesday’s game between the Knicks and 76ers:

  • Moneyline: Rotoworld Bet is inclined to play on the 76ers Moneyline

  • Diffusion: Rotoworld Bet is leaning towards the 76ers +6.5 ATS

  • Total: Rotoworld Bet is leaning towards a bet on the total game UNDER 215.5

Want even more top NBA bets and predictions from our expert staff and tools? Check it out Expert NBA Predictions Page from NBC Sports for money line, spread and over/under bets for every game on today’s schedule!

If you’re looking for more trends and key statistics on the spread, moneyline and total for every single game scheduled today, check out our NBA Top Trends Tool on NBC Sports!

Follow our experts on social media to stay up to date on all the latest staff content:

  • Jay Croucher (@croucherJD)

  • Drew Dinsick (@whale_capper)

  • Vaughn Dalzell (@VmoneySports)

  • Trysta Krick (@Trysta_Krick)

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