Magic vs Pistons NBA Playoff Game 2 Predictions: Odds, Recent Stats, Trends and Best Bets for April 22

The Detroit Pistons attempt to keep home court in Game 2 after their surprising Game 1 loss to the Orlando Magic, 112-101.

Detroit has lost 10 consecutive home games in the playoffs, but is a heavy favorite in Game 2. The Pistons were led by Cade Cunningham’s 39 points, but only he and Tobias Harris (17) scored more than eight points for Detroit.

Announcement

All five Orlando starters scored 16 or more points with the Magic’s bench putting up 20 total points. The Magic led at the end of every quarter and put up impressive numbers for a road team in Game 1, with the exception of their three-point shooting (10/34, 29%), which will need to improve as the series goes on.

Let’s take a closer look at tonight’s matchup and take into consideration lineups, injuries and other factors that affect the line and total.

We’ve got all the information and analysis you need to know ahead of the game, including the latest information on how to get tip-offs, odds courtesy of DraftKings recent team performances, player statistics and of course our predictions, select the best bets for the game from our modeling tools and expert staff.

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Announcement

Game details and how to watch live: Magic vs. Pistons

• Date: Tuesday 21 April 2026

• Site: Arena of the Little Caesars

• Network/Streaming: NBC/Peacock

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Game Odds: Magic vs. Pistons

Latest Monday odds courtesy of DraftKings:

• Moneyline: Detroit Pistons (-410), Orlando Magic (+320)

This game opened Pistons -9.5 with the total set at 218.5.

Be sure to check it out DraftKings for all the latest game odds and player tips for every game this week on the NBA schedule!

Expected Starting Lineups: Magic vs. Pistons

Orlando Magic

Announcement

Detroit Pistons

Injury Report: Pistons vs. Magic

Orlando Magic

• Jonathan Issac (knee) he is listed as questionable for Game 2

Detroit Pistons

Important stats, trends and insights: Pistons vs. Magic

• Detroit is 21-20 ATS as the home team

• Detroit is 44-38-1 for the Under

• Detroit is the 18-14 home favorite against the Under

• Detroit is 22-19 for the hosts Under

• Orlando is 19-22 ATS as a road team

• Orlando is 45-40 at the Over

• Orlando is 21-20 for the Under on the road

• Orlando is 12-10 in the Over as an underdog

Rotoworld best bet

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Our model calculates projections on every moneyline, spread and over/under bet for every game on the NBA schedule based on data such as recent performances, head-to-head player comparisons, trend information and projected game totals.

Once the model has finished running, we place its projections next to the final betting lines for the game to arrive at a relative confidence level for each bet.

Announcement

Here are the best bets our model predicts for Tuesday’s Magic and Pistons game:

• Moneyline: Rotoworld Bet leans towards a Pistons Moneyline bet

• Diffusion: Rotoworld Bet leans towards a bet on the Pistons -8.5 ATS

• Total: Rotoworld Bet is leaning towards a bet on the total game UNDER 218.5

Want even more top NBA bets and predictions from our expert staff and tools? Check it out Expert NBA Predictions Page from NBC Sports for money line, spread and over/under bets for every game on today’s schedule!

If you’re looking for more trends and key statistics on the spread, moneyline and total for every single game scheduled today, check out our NBA Top Trends Tool on NBC Sports!

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